Because buildings are the engine of our economy, we should do whatever we can to reduce the risk of indoor transmission. As we consider further opening our economy, and therefore occupy more buildings, we should begin routine testing of our buildings for SARS-CoV-2. Concurrently, we should implement a bundle of building measures following guidance in our recent paper, that of the AIA, and of the ASHRAE. We should continue with routine testing for SARS-CoV-2 in our buildings to generate an evidence-based approach to reduce potential disease transmission risks indoors.